Tutto DSpace

Sfoglia per Soggetto "Peptide Library"

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    • REPLACE: A strategy for iterative design of cyclin-binding groove inhibitors 

      Andrews, M. J. I.; Kontopidis, G.; McInnes, C.; Plater, A.; Innes, L.; Cowan, A.; Jewsbury, P.; Fischer, P. M. (2006)
      We describe a drug-design strategy termed REPLACE (REplacement with Partial Ligand Alternatives through Computational Enrichment) in which nonpeptidic surrogates for specific determinants of known peptide ligands are ...